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Week 6 Flex Rankings for Fantasy Football

Week 6 is the first one of the 2022 NFL season in which bye weeks are prevalent. Cue the collective groans from the fantasy community, but I like it. I know, I’m a weirdo. But hear me out. This is the time of the year when roster depth and savvy management begin to have a greater impact. Add that to the weekly dose of injuries and matchup data, and the fun is truly about to commence. Because of the byes, I have fewer players than normal in this week’s Flex rankings. Usually, I have a little over 300 players ranked. This week, that number is closer to 275. That should still be enough to help you with any lineup decisions you may have but comment below with any specific questions you may have. Now let’s get to the Week 6 Flex rankings!

Running Back Notes

Rashaad Penny suffered a broken fibula in Week 5 and will miss the rest of the season. It is a tough blow for Penny, who has dealt with his fair share of injuries during his brief NFL career. Seattle has shown surprising competence on the offensive end so far this year. Their offensive line has provided an average of 1.78 yards per rush before contact which is the highest rate in the league. It now appears that Kenneth Walker will be the primary beneficiary of that cushion going forward. Penny was a top-24 half-PPR back through five weeks, and I would expect Walker to carry a similar designation. I would certainly start Walker as a Week 6 Flex if you already have two solid running backs on your roster. DeeJay Dallas can also make some noise, but I would hold off on starting him unless you are in a pinch.

Like Walker, Rhamondre Stevenson was thrust into a larger role last week when Damien Harris was taken out by a hamstring injury. Stevenson, who had posted decent results through four weeks (RB29), was last week’s RB14. And that ranking doesn’t do his effort justice. Stevenson amassed 161 rushing yards on 25 carries in New England’s victory over Detroit. He also chipped in a pair of receptions. Harris is likely to miss this week’s contest against the Cleveland Browns. If that is the case, Stevenson goes from potential Flex play to no-brainer RB1. The Browns have allowed opposing running backs to gash them at a 5.8 yards per carry clip. Harris did take part in a limited practice, but I do not expect him to play this week.

Raheem Mostert is another AFC East running back whose value continues to climb. The former 49er has earned at least 14 touches in three of Miami’s last four games. During that stretch, Mostert has been the overall RB23. Last week he dominated the work in the backfield, rushing for 113 yards and out-touching Chase Edmonds 19-1. Mostert’s Achilles’ heel has always been durability, not talent. Sure enough, he popped up on the injury report this week with a knee issue. It could just be simple wear and tear, but this could be something to monitor given his history. For now, I have Mostert as an RB2 but pay attention to his participation in practice as the week rolls on. If Mostert is good to go, I would not trust Edmonds as a Week 6 Flex. I would hold him though if Mostert is bitten once again by the injury bug.

Not every running back is seeing their value increase as we approach Week 6. Najee Harris of the Pittsburgh Steelers has yet to post as many as 12 fantasy points (half-PPR scoring) in a single game this season after reaching that threshold in 13 of 17 contests in his rookie season a year ago. I do not expect his fortunes to suddenly turn around this week against the Tampa Bay Buccaneers. The Bucs have allowed the fewest fantasy points in the NFL to opposing running backs this year. Steelers coach Mike Tomlin has also expressed a desire to continue to incorporate undrafted rookie Jaylen Warren into the fold. I currently have Harris ranked as a mid-range RB2, but that is probably overly optimistic given the circumstances. It may be a hard pill to swallow, but I would seriously consider benching Harris this week.

Wide Receiver Notes

The most anticipated matchup of the week pits the Kansas City Chiefs against the Buffalo Bills in a rematch of last year’s instant classic playoff contest. There will be no shortage of Week 6 Flex options in this contest. Of course, you are starting the usual suspects such as Stefon Diggs and Gabe Davis. I expect both Juju Smith-Schuster and Marquez Valdes-Scantling to be solid Flex players in this matchup. Buffalo is still dealing with some injuries in their secondary, and Patrick Mahomes will be tasked with matching Josh Allen point for point. Both Chiefs wideouts are averaging just north of 50 receiving yards per game so far this year but have yet to score. I believe that at least one of them will score on Sunday, and I would not hesitate to start either player depending on your other options.

This could be a game where some ancillary players get some fantasy love as well. Mecole Hardman posted season-highs with four receptions and 73 yards in Monday night’s come-from-behind victory. I have Hardman outside my top 60 wide receivers this week, but you could do worse than chasing points in what should be a very high-scoring affair. On the other side, I feel that Isaiah McKenzie is a top-100 Flex option, and he could also be an interesting play this week. McKenzie cleared the league’s concussion protocol and should be good to go Sunday. He has scored in three of four games this year. In his absence last week, rookie Khalil Shakir had 75 yards and a score. Assuming no further setbacks for McKenzie, I would not trust Shakir in fantasy lineups this week.

Alec Pierce has moved his way up the pecking order in Indianapolis in recent weeks. The second-round rookie has eclipsed the 60-yard mark in three straight, including 80-plus yards in his last two outings. Among receivers who have run at least 100 routes, Pierce’s 2.06 yards per route run is the 17th-best. The Colts placed fellow wideout, Ashton Dulin, on injured reserve this week, which should cement Pierce’s status for the time being. A Week 6 matchup with Jacksonville will be an interesting test for Pierce. Their weak link so far has been slot corner Darious Williams, but Pierce does not usually operate out of the slot. Instead, he will likely have to deal with Shaquill Griffin and Tyson Campbell. I expect Pierce will be up to the task, and I believe he is a viable Week 6 Flex play.

I mentioned Allen Robinson’s disappearing act in this column last week, and that trend continued once again. Robinson mustered just 12 receiving yards on a handful of targets. Sadly his 2.7 half-PPR points were the third-highest total he has posted in five games as a Ram. Robinson has been dropped in several leagues and is now available in 11 percent of Fantrax leagues. I would entertain the thought of grabbing him off the wire if I have an obvious drop. Otherwise, I don’t have an issue with leaving him there for another week. The Rams have a bye next week, followed by a difficult matchup with San Francisco in Week 8. Perhaps Sean McVay uses the bye to figure out how to better incorporate Robinson into their passing hierarchy. But fantasy managers can safely leave him on the bench until that happens.

Through the first four games of the season, the New York Jets had six different players with at least 15 receptions. No other team in the NFL had more than three such players. While this ambiguous approach may be helpful in real life, that is not the case for our purposes. This is especially true for those who invested an early draft pick on Elijah Moore. Moore has yet to score more than 7.4 fantasy points in a single game this season. Unless something changes from a schematic or injury standpoint, fantasy managers cannot trust Moore in lineups. I currently have Moore ranked third among Jets receivers this week behind Garrett Wilson and Corey Davis, but none of them are must-starts. I consider all three WR4-WR5s in 12-team leagues in any given week.

Tight End Notes

As per usual, only six of my top 90 Week 6 Flex options are tight ends. After that, it’s a matter of personal preference more than anything. I preached patience with Kyle Pitts last week, and then he ended up not playing due to injury. Pitts is expected to play this week, but the matchup versus San Francisco is not kind. I would still start him where possible because his upside is quite high compared to his contemporaries, but I can understand those who want a “show me” week out of Pitts first.

The Seattle Seahawks and Arizona Cardinals have ceded the most fantasy points to opposing tight ends so far this season. As luck would have it, the two face off on Sunday afternoon. You don’t need me to tell you to start Zach Ertz. Ertz enters the week as the overall TE6, and Arizona will be without DeAndre Hopkins for one more week. Ertz should see plenty of opportunities in a game with an implied total of 50.5 points. As for Seattle, it is Will Dissly (and not Noah Fant) who has produced TE1 numbers through five weeks. The volume is still a little fluky for my liking, however, Dissly has been targeted just 14 times in five games, while Fant has earned 13 targets. I have Fant ranked slightly ahead of Dissly this week, but both are currently outside my top 15 tight ends.

Week 6 Fantasy Football Flex Rankings

More Week 6 Rankings: QB | RB | WR | TE | Flex Rankings

1Cooper KuppLAWR1CAR
2Stefon DiggsBUFWR2@KC
3Saquon BarkleyNYGRB1BLT
4Christian McCaffreyCARRB2@LA
5Justin JeffersonMINWR3@MIA
6Austin EkelerLACRB3DEN
7Rhamondre StevensonNERB4@CLV
8Deebo SamuelSFWR4@ATL
9Jonathan TaylorINDRB5JAX
10Alvin KamaraNORB6CIN
11Nick ChubbCLVRB7NE
12Leonard FournetteTBRB8@PIT
13Marquise BrownARZWR5@SEA
14Aaron JonesGBRB9NYJ
15Ja'Marr ChaseCINWR6@NO
16Mark AndrewsBLTTE1@NYG
17Travis KelceKCTE2BUF
18Dalvin CookMINRB10@MIA
19Tyreek HillMIAWR7MIN
20Joe MixonCINRB11@NO
21Breece HallNYJRB12@GB
22Mike EvansTBWR8@PIT
23D.K. MetcalfSEAWR9ARZ
24Tyler LockettSEAWR10ARZ
25Jeff Wilson Jr.SFRB13@ATL
26David MontgomeryCHIRB14WAS
27A.J. BrownPHIWR11DAL
28Courtland SuttonDENWR12@LAC
29CeeDee LambDALWR13@PHI
30Jaylen WaddleMIAWR14MIN
31Miles SandersPHIRB15DAL
32Kenneth Walker IIISEARB16ARZ
33Melvin Gordon IIIDENRB17@LAC
34Raheem MostertMIARB18MIN
35Najee HarrisPITRB19TB
36Gabriel DavisBUFWR15@KC
37Michael Pittman Jr.INDWR16JAX
38Chris GodwinTBWR17@PIT
39Christian KirkJAXWR18@IND
40Amari CooperCLVWR19NE
41Mike WilliamsLACWR20DEN
42Allen LazardGBWR21NYJ
43Clyde Edwards-HelaireKCRB20BUF
44Ezekiel ElliottDALRB21@PHI
45Curtis SamuelWASWR22@CHI
46Diontae JohnsonPITWR23TB
47Tee HigginsCINWR24@NO
48DeVonta SmithPHIWR25DAL
49Adam ThielenMINWR26@MIA
50Drake LondonATLWR27SF
51Tyler HigbeeLATE3CAR
52Zach ErtzARZTE4@SEA
53Devin SingletaryBUFRB22@KC
54A.J. DillonGBRB23NYJ
55Kareem HuntCLVRB24NE
56Jakobi MeyersNEWR28@CLV
57D.J. MooreCARWR29@LA
58Cam AkersLARB25CAR
59Keenan AllenLACWR30DEN
60Romeo DoubsGBWR31NYJ
61Brandon AiyukSFWR32@ATL
62Chris OlaveNOWR33CIN
63James RobinsonJAXRB26@IND
64Terry McLaurinWASWR34@CHI
65Jerry JeudyDENWR35@LAC
66J.K. DobbinsBLTRB27@NYG
67George KittleSFTE5@ATL
68Dallas GoedertPHITE6DAL
69Rondale MooreARZWR36@SEA
70JuJu Smith-SchusterKCWR37BUF
71Marquez Valdes-ScantlingKCWR38BUF
72Travis EtienneJAXRB28@IND
73Rashod BatemanBLTWR39@NYG
74James ConnerARZRB29@SEA
75Eno BenjaminARZRB30@SEA
76Garrett WilsonNYJWR40@GB
77Tyler AllgeierATLRB31SF
78Darnell MooneyCHIWR41WAS
79Michael ThomasNOWR42CIN
80Tony PollardDALRB32@PHI
81Alec PierceINDWR43JAX
82Marvin Jones Jr.JAXWR44@IND
83Zay JonesJAXWR45@IND
84Tyler BoydCINWR46@NO
85George PickensPITWR47TB
86Isaiah McKenzieBUFWR48@KC
87Randall CobbGBWR49NYJ
88Darrell HendersonLARB33CAR
89Corey DavisNYJWR50@GB
90Michael GallupDALWR51@PHI
91David NjokuCLVTE7NE
92Michael CarterNYJRB34@GB
93Antonio GibsonWASRB35@CHI
94Kyle PittsATLTE8SF
95Devin DuvernayBLTWR52@NYG
96Chase ClaypoolPITWR53TB
97Russell GageTBWR54@PIT
98Allen Robinson IILAWR55CAR
99Donovan Peoples-JonesCLVWR56NE
100Gerald EverettLACTE9DEN
101Elijah MooreNYJWR57@GB
102Pat FreiermuthPITTE10TB
103Richie James Jr.NYGWR58BLT
104Hayden HurstCINTE11@NO
105Julio JonesTBWR59@PIT
106Rachaad WhiteTBRB36@PIT
107J.D. McKissicWASRB37@CHI
108Robert TonyanGBTE12NYJ
109Brian RobinsonWASRB38@CHI
110Robbie AndersonCARWR60@LA
111Dawson KnoxBUFTE13@KC
112Josh PalmerLACWR61DEN
113Mike BooneDENRB39@LAC
114Noah BrownDALWR62@PHI
115Irv Smith Jr.MINTE14@MIA
116Jarvis LandryNOWR63CIN
117K.J. OsbornMINWR64@MIA
118Nyheim HinesINDRB40JAX
119Khalil HerbertCHIRB41WAS
120Mecole HardmanKCWR65BUF
121Evan EngramJAXTE15@IND
122Bennett SkowronekLAWR66CAR
123Alexander MattisonMINRB42@MIA
124Olamide ZaccheausATLWR67SF
125DeVante ParkerNEWR68@CLV
126Noah FantSEATE16ARZ
127Jerick McKinnonKCRB43BUF
128A.J. GreenARZWR69@SEA
129Chase EdmondsMIARB44MIN
130Kendrick BourneNEWR70@CLV
131Joshua KelleyLACRB45DEN
132Marcus JohnsonNYGWR71BLT
133Cole KmetCHITE17WAS
134Tyler ConklinNYJTE18@GB
135Darius SlaytonNYGWR72BLT
136DeeJay DallasSEARB46ARZ
137Khalil ShakirBUFWR73@KC
138Daniel BellingerNYGTE19BLT
139Will DisslySEATE20ARZ
140Parris CampbellINDWR74JAX
141Equanimeous St. BrownCHIWR75WAS
142Kenneth GainwellPHIRB47DAL
143Caleb HuntleyATLRB48SF
144Mark Ingram IINORB49CIN
145Cameron BrateTBTE21@PIT
146Nelson AgholorNEWR76@CLV
147Mo Alie-CoxINDTE22JAX
148Samaje PerineCINRB50@NO
149Hunter HenryNETE23@CLV
150Kadarius ToneyNYGWR77BLT
151Shi SmithCARWR78@LA
152Jauan JenningsSFWR79@ATL
153Dalton SchultzDALTE24@PHI
154Jaylen WarrenPITRB51TB
155Tevin ColemanSFRB52@ATL
156Mike GesickiMIATE25MIN
157Tyquan ThorntonNEWR80@CLV
158Christian WatsonGBWR81NYJ
159Tre'Quan SmithNOWR82CIN
160Eric SaubertDENTE26@LAC
161Dyami BrownWASWR83@CHI
162Dante PettisCHIWR84WAS
163Scotty MillerTBWR85@PIT
164Kylen GransonINDTE27JAX
165Juwan JohnsonNOTE28CIN
166K.J. HamlerDENWR86@LAC
167Darrel WilliamsARZRB53@SEA
168Harrison BryantCLVTE29NE
169Marquez CallawayNOWR87CIN
170Cade OttonTBTE30@PIT
171Breshad PerrimanTBWR88@PIT
172David SillsNYGWR89BLT
173DeAndre CarterLACWR90DEN
174Demarcus RobinsonBLTWR91@NYG
175Quez WatkinsPHIWR92DAL
176Trent SherfieldMIAWR93MIN
177James CookBUFRB54@KC
178Cedrick WilsonMIAWR94MIN
179John BatesWASTE31@CHI
180Isiah PachecoKCRB55BUF
181Pierre Strong Jr.NERB56@CLV
182Avery WilliamsATLRB57SF
183Jonnu SmithNETE32@CLV
184Wan'Dale RobinsonNYGWR95BLT
185Zack MossBUFRB58@KC
186Skyy MooreKCWR96BUF
187Justice HillBLTRB59@NYG
188Gus EdwardsBLTRB60@NYG
189Adam TrautmanNOTE33CIN
190Isaiah LikelyBLTTE34@NYG
191KhaDarel HodgeATLWR97SF
192Quintin MorrisBUFTE35@KC
193Marquise GoodwinSEAWR98ARZ
194Kyle JuszczykSFRB61@ATL
195Latavius MurrayDENRB62@LAC
196Albert OkwuegbunamDENTE36@LAC
197Braxton BerriosNYJWR99@GB
198Matt BreidaNYGRB63BLT
199Laviska ShenaultCARWR100@LA
200Tommy TrembleCARTE37@LA
201C.J. UzomahNYJTE38@GB
202Myles GaskinMIARB64MIN
203Durham SmytheMIATE39MIN
204Deon JacksonINDRB65JAX
205Colby ParkinsonSEATE40ARZ
206Sony MichelLACRB66DEN
207J.J. TaylorNERB67@CLV
208Cam SimsWASWR101@CHI
209Tanner HudsonNYGTE41BLT
210Jelani WoodsINDTE42JAX
211Zach GentryPITTE43TB
212Parker HesseATLTE44SF
213Greg DortchARZWR102@SEA
214Ian ThomasCARTE45@LA
215Johnny MundtMINTE46@MIA
216D'Wayne EskridgeSEAWR103ARZ
217Cole TurnerWASTE47@CHI
218Tutu AtwellLAWR104CAR
219Ray-Ray McCloud IIISFWR105@ATL
220Jalen TolbertDALWR106@PHI
221Jamal AgnewJAXWR107@IND
222Noah GrayKCTE48BUF
223David BellCLVWR108NE
224Donald ParhamLACTE49DEN
225Keaontay IngramARZRB68@SEA
226Jake FergusonDALTE50@PHI
227Boston ScottPHIRB69DAL
228Brandon PowellLAWR109CAR
229Damiere ByrdATLWR110SF
230Anthony FirkserATLTE51SF
231Justin WatsonKCWR111BUF
232Terrace Marshall Jr.CARWR112@LA
233Bryan EdwardsATLWR113SF
234Peyton HendershotDALTE52@PHI
235Ihmir Smith-MarsetteCHIWR114WAS
236James ProcheBLTWR115@NYG
237Patrick RicardBLTRB70@NYG
238Mike ThomasCINWR116@NO
239Kenny GolladayNYGWR117BLT
240Ryan GriffinCHITE53WAS
241Marcedes LewisGBTE54NYJ
242Trey McBrideARZTE55@SEA
243Joe FortsonKCTE56BUF
244Tommy SweeneyBUFTE57@KC
245Jordan MasonSFRB71@ATL
246Anthony SchwartzCLVWR118NE
247Ross DwelleySFTE58@ATL
248Tony Jones Jr.SEARB72ARZ
249Tre' McKittyLACTE59DEN
250Greg DulcichDENTE60@LAC
251Zach PascalPHIWR119DAL
252Brycen HopkinsLATE61CAR
253Kendall HintonDENWR120@LAC
254Chuba HubbardCARRB73@LA
255Giovanni RicciCARTE62@LA
256Chris MyarickNYGRB74BLT
257Dan ArnoldJAXTE63@IND
258D'Ernest JohnsonCLVRB75NE
259River CracraftMIAWR121MIN
260Malcolm BrownLARB76CAR
261Taysom HillNOTE64CIN
262Logan ThomasWASTE65@CHI
263Jalen ReagorMINWR122@MIA
264D'Onta ForemanCARRB77@LA
265Zander HorvathLACRB78DEN
266Trestan EbnerCHIRB79WAS
267Kendall BlantonLATE66CAR
268Alec IngoldMIARB80MIN
269Miles BoykinPITWR123TB
270Velus JonesCHIWR124WAS
271Demetric FeltonCLVWR125NE
272Gary BrightwellNYGRB81BLT
273JaMycal HastyJAXRB82@IND
274Mitchell WilcoxCINTE67@NO
275Dezmon PatmonINDWR126JAX
276Benny Snell Jr.PITRB83TB
277Trevon WescoCHITE68WAS
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